Microbial Eukaryote Evolution and Ecology

Eukaryotes are organisms with complex cells that arose from the fusion of their bacterial and archaeal predecessors. Plants and animals are the most prominent examples to the human eye, but the vast majority of eukaryotes (incl. protists/algae), like their common ancestor, are microscopic unicellular life forms with intriguing evolutionary history and ecological behaviors. It is our broad interest to understand how different microbial eukaryotes came to be what they are today and what roles they play in various environments on Earth.

Our research focuses on two main topics:

Microalgal genomics
Unicellular algae in the ocean are characterized by high growth and turnover rate and account for half of the photosynthetic production on our planet. Currently we are specifically interested in coccolithophores – a group of microalgae capable of converting CO2 and calcium into calcite (chalk) platelets that can be sedimented at the bottom of the ocean. The best known of these armored phytoplankton, Emiliania huxleyi, is a globally distributed species that forms massive annual blooms (dramatic changes in population size) and has diploid and haploid phases with obscure transitions. Using state-of-the-art sequencing technology, omic and bioinformatic methods, and single-cell approaches, our goal is to elucidate the dynamics of coccolithophore genomes across time and space.

Giant viruses and their eukaryotic hosts
Viruses are found in almost all living things and ecosystems. The nucleocytoplasmic large DNA viruses include the largest viruses known today in terms of physical and genome sizes (many even larger than small bacterial genomes) and infect diverse hosts ranging from vertebrates (e.g., African swine fever virus), invertebrates, amoebae, and various algae in both freshwater and seawater. Major themes in our lab include how the large genomes of giant viruses are organized and expressed, as well as how their genome regulation has changed through the long history of coevolution with their eukaryotic hosts.

From time to time we have open positions for postdocs, PhD students, master students and research associates. If you are interested in joining us, please contact Chuan Ku by email.

國際

• 2022 歐洲分子生物學組織(EMBO)全球研究學者 - 歐洲分子生物組織(EMBO)

國內

• 2025 2030跨世代年輕學者–國際年輕傑出學者研究計畫 - 國家科學及技術委員會
• 2024 國立臺灣大學教學優良獎 - 國立臺灣大學
• 2022 新秀獎 - 臺灣植物學會
• 2021 年輕學者創新獎 - 財團法人傑出人才發展基金會
• 2021 前瞻計畫 - 中央研究院